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کمک آنلاین
Characteristic Description
Active Ingredient Vardenafil
Dosage Form Tablet
Strength ۲۰ mg
Intended Use Erectile Dysfunction
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Chemical Structure

The core component of Super Levitra, vardenafil, stands among the phosphodiesterase type 5 inhibitors. This class of compounds boasts a heterocyclic core with a sulfur atom, bolstered by adjacent aromatic groups. Vardenafil’s structural identity allows it to inhibit the breakdown of cyclic guanosine monophosphate (cGMP). This action underlies its potency in addressing erectile dysfunction.

Vardenafil’s configuration offers enhanced affinity for its target enzyme, PDE5. Its specificity minimizes interference with PDE6, which resides predominantly in the retina. This precise interaction profile curtails visual side effects seen with similar agents. The design of vardenafil optimizes it for rapid uptake, while sustaining active concentrations in the bloodstream. The ability to displace bound water molecules from its binding pocket augments its efficacy and bioavailability.

The spatial arrangement and electronic properties of vardenafil confer a robust interaction with the active site of PDE5. This structure permits a snug fit, which is essential for its therapeutic effect. The chemical framework of vardenafil continues to inspire the synthesis of novel PDE5 inhibitors with improved therapeutic profiles.

Off-Label Uses

Though primarily endorsed for erectile dysfunction, Super Levitra’s vardenafil has surfaced in diverse contexts. A burgeoning area of interest lies in the management of pulmonary arterial hypertension (PAH). This condition involves elevated blood pressure in the lungs’ arteries, where vardenafil’s vasodilatory effects might yield benefit.

Vardenafil is occasionally explored in Raynaud’s phenomenon, a vascular disorder typified by episodic blood flow reduction to extremities. In these cases, the aim is to harness its capacity to improve blood flow. Some anecdotal evidence suggests efficacy, though substantial clinical trials remain scant.

Explorations into benign prostatic hyperplasia (BPH) have also occurred. Here, the potential alleviation of urinary symptoms could be linked to enhanced pelvic blood circulation. Despite these promising avenues, comprehensive validation in large-scale studies is still pending.

FDA-Approved Indications

The United States Food and Drug Administration (FDA) has endorsed Super Levitra for treating erectile dysfunction. This approval underscores its role in the context of sexual health and therapeutic intervention. Its efficacy in improving penile rigidity during arousal remains its primary indication.

Clinical trials, spearheaded by the FDA, substantiated vardenafil’s effectiveness in achieving this outcome. These investigations also highlighted its safety profile, leading to a favorable risk-benefit ratio. The approval process involved multiple phases, including dose-ranging studies and placebo-controlled trials.

Through rigorous scrutiny, Super Levitra emerged as a viable option in the therapeutic landscape. Its inclusion among FDA-approved medications signifies a well-documented, predictable pharmacodynamic effect. Healthcare providers rely on this data when prescribing, ensuring a standardized treatment approach.

Cautions with Other Medicines

Super Levitra interacts with various pharmaceuticals. Co-administration with nitrates, often used in angina, can precipitate life-threatening hypotension. This contraindication stems from the synergistic effect on vascular smooth muscle.

CYP3A4 inhibitors, such as ketoconazole, may elevate vardenafil plasma levels, heightening adverse event risk. A dose adjustment or careful monitoring is warranted. Conversely, inducers like rifampin could diminish therapeutic effects.

Alpha-blockers, used in hypertension and BPH, demand cautious combination due to potential blood pressure drops. A temporal separation of dosages may mitigate risks. Other antihypertensives should be evaluated on a case-by-case basis, balancing benefit and hazard.

Effects of Super Levitra

The primary action of Super Levitra manifests in its facilitation of penile erections. By preventing cGMP degradation, it sustains smooth muscle relaxation and increased blood inflow. This physiological mechanism underpins its therapeutic success in erectile dysfunction.

Clinical observations frequently cite rapid onset, often within 30 minutes. Duration of effect may extend up to five hours, providing a window for sexual activity. Its bioavailability allows for predictable and consistent performance, catering to patient needs.

Reported side effects are typically mild, including headache, facial flushing, and nasal congestion. Rare but serious reactions, such as priapism or sudden hearing loss, necessitate immediate medical attention. Routine follow-up ensures continued efficacy and safety.

Is Non-Prescription Super Levitra Available?

Super Levitra is categorized as a prescription medication. It necessitates a licensed healthcare professional’s authorization. This regulation stems from its potent pharmacological actions and interaction profile.

Counterfeit products often masquerade as non-prescription alternatives, posing significant health risks. These unregulated sources lack stringent quality control and may contain harmful substances. Patients should remain vigilant against such fraudulent practices.

Pharmacies, both brick-and-mortar and online, provide legitimate access when armed with a prescription. This ensures authenticity and adherence to regulatory standards. A healthcare provider’s guidance is invaluable in optimizing therapy and minimizing potential complications.

Parameter Details
Absorption Rapid
Peak Plasma Concentration ۳۰ to 120 minutes
Metabolism Hepatic via CYP3A4
Excretion Fecal (91%), Renal (6%)

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