خیریه زنجیر مهربانی
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کمک آنلاین
Characteristic Details
Active Ingredients Amiloride Hydrochloride and Furosemide
Strength ۵ mg / 40 mg
Form Tablet
Indications Fluid retention, Hypertension
Administration Oral
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Pharmacokinetics

Frumil, a diuretic, functions by increasing urine output. Amiloride blocks sodium channels in renal epithelial cells. It conserves potassium by reducing its excretion. Furosemide works in the loop of Henle. It inhibits sodium and chloride reabsorption, augmenting urine formation. Absorption occurs rapidly post-oral administration. Peak plasma concentrations arise within 1-2 hours. Amiloride exhibits a half-life of 6-8 hours. Furosemide’s half-life spans 1-1.5 hours. Metabolism is minimal for both agents. Renal excretion is primary for furosemide, while amiloride excretes unchanged in urine.

Dosage Information

Standard adult dosage for Frumil is 5 mg Amiloride and 40 mg Furosemide once daily. The regimen suits fluid retention linked to congestive heart failure or cirrhosis. Doses may vary based on individual response and condition severity. Monitor electrolytes regularly during therapy. Adjustments might be necessary for renal impairment. Frumil should be taken in the morning. This minimizes nocturnal urination. Consistent dosing time enhances treatment adherence. Avoid altering the prescribed dosage without medical consultation.

Who Can and Cannot Take Frumil

Frumil suits adults requiring fluid management or hypertension control. It benefits those with cardiac or hepatic issues. Avoid in patients with anuria or severe renal failure. Contraindications include hypersensitivity to sulfonamides. Caution in patients with diabetes or gout. Electrolyte imbalances warrant careful monitoring. Pediatric and adolescent use lacks sufficient data. Pregnant and breastfeeding women should avoid Frumil unless necessary. Discuss potential risks and benefits with a healthcare provider.

Cautions with Other Medicines

Concomitant use of Frumil with certain drugs may alter effects. Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce diuretic efficacy. Combining with antihypertensives might potentiate blood pressure reduction. Monitor for hypokalemia with corticosteroids or other diuretics. Risk of ototoxicity increases with aminoglycosides. Lithium levels may rise when taken with Frumil. Regular lab tests help in preventing interactions. Always inform your healthcare provider about all concurrent medications.

Side Effects

Frumil can cause side effects like dizziness or dehydration. Electrolyte imbalances such as hyponatremia or hypokalemia occur. Some may experience gastrointestinal disturbances. Rarely, patients report hearing problems or skin reactions. Serious reactions include severe abdominal pain, jaundice, or signs of kidney dysfunction. Inform your doctor about any unexpected symptoms. Most side effects are manageable with dose adjustments. Regular monitoring mitigates adverse outcomes.

Purchasing Frumil Without a Prescription

Frumil is a prescription medication. It requires medical oversight. Online platforms offer medications without prescriptions. Such purchases carry risks. Counterfeit or substandard products may prevail. Incorrect dosing can lead to serious health issues. Consult a healthcare professional before initiating treatment. An accurate diagnosis ensures appropriate therapy. Adhere to legal and medical guidelines when obtaining medications. Your health should always be a priority.

Parameter Description
Pharmacokinetic Class Diuretic
Route of Administration Oral
Monitoring Requirements Electrolytes, Renal Function

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